
Anethole trithione
CAS No. 532-11-6
Anethole trithione( Anetholtrithion | Anethole trithione )
Catalog No. M14895 CAS No. 532-11-6
Anethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of Y.
Purity : >98% (HPLC)






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Biological Information
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Product NameAnethole trithione
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NoteResearch use only, not for human use.
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Brief DescriptionAnethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of Y.
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DescriptionAnethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of Y.(In Vitro):Anethole trithione, a slow-releasing H2S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.(In Vivo):Chronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.
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In VitroAnethole trithione, a slow-releasing H2S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.
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In VivoChronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.
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SynonymsAnetholtrithion | Anethole trithione
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number532-11-6
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Formula Weight240.35
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Molecular FormulaC10H8OS3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESS=C1SSC(C2=CC=C(OC)C=C2)=C1
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Chemical Name3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ukai Y, et al. Arzneimittelforschung. 1988 Oct; 38(10):1460-5.
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