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Anethole trithione
CAS No. 532-11-6
Anethole trithione( Anetholtrithion | Anethole trithione )
Catalog No. M14895 CAS No. 532-11-6
Anethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of Y.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 52 | In Stock |
|
| 500MG | 81 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAnethole trithione
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NoteResearch use only, not for human use.
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Brief DescriptionAnethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of Y.
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DescriptionAnethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of Y.(In Vitro):Anethole trithione, a slow-releasing H2S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.(In Vivo):Chronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.
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In VitroAnethole trithione, a slow-releasing H2S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.
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In VivoChronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.
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SynonymsAnetholtrithion | Anethole trithione
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number532-11-6
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Formula Weight240.35
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Molecular FormulaC10H8OS3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESS=C1SSC(C2=CC=C(OC)C=C2)=C1
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Chemical Name3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SH-42
SH-42 is a human Δ24-dehydrocholesterol reductase (DHCR24) inhibitor (IC50: 42 nM) that is selective and highly potent in inducing an increase in plasma desmethylferricinol levels.
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Lorundrostat
Lorundrostat (MT-4129) is an aldosterone synthase inhibitor with antihypertensive activity that lowers systolic blood pressure.
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CALP1
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). Shown to protect pancreatic acinar cells from gossypol induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo.
